Protamine Zinc Insulin
Full Form of PZI
What is PZI?
Protamine Zinc Insulin (PZI) is a long-acting insulin formulation used primarily for the management of diabetes mellitus. It combines insulin with protamine and zinc to slow absorption, providing a prolonged duration of action of 24 to 36 hours. In India, PZI has historically been utilized in public health programs and rural areas due to its affordability and once-daily dosing convenience, though its use has declined with the advent of modern analogs like insulin glargine. It is typically administered subcutaneously for type 1 and type 2 diabetes patients requiring basal insulin coverage. PZI is occasionally referenced in medical entrance exams such as NEET PG and in pharmacy curricula, where students compare its pharmacokinetics with other insulins. Its cloudy appearance requires careful resuspension before injection. While not as common in urban Indian hospitals today, PZI remains available in some government supply chains for cost-effective diabetes care.
PZI का फुल फॉर्म
प्रोटामिन जिंक इंसुलिन
Example
The patient with type 1 diabetes was switched from regular insulin to PZI for better overnight glucose control.