Full formMedical & Health
PDXstands forPatient-Derived Xenograft
Full Form of PDX
What is PDX?
A patient-derived xenograft (PDX) is a preclinical cancer model where tumor tissue from a patient is implanted into immunodeficient mice. This model preserves the genetic, molecular, and histological features of the original tumor, making it a powerful tool for studying cancer biology, drug response, and resistance mechanisms. In India, PDX models are increasingly used by research centres like the Tata Memorial Centre and the Indian Institute of Science to evaluate therapies for cancers prevalent in the country, such as oral, breast, and cervical cancers. They are also employed in personalized medicine to predict treatment outcomes for individual patients. PDX models are typically used in academic laboratories and biotech companies, often in collaboration with pharmaceutical firms for drug development. For students of medicine, biotechnology, and life sciences, understanding PDX is important for topics in oncology, molecular biology, and translational research, and may appear in examinations such as NEET PG, CSIR NET, and GATE.
PDX का फुल फॉर्म
रोगी-व्युत्पन्न क्सीनोग्राफ्ट
Example
The team at the cancer institute established a PDX model from the patient's oral tumour to test the efficacy of a novel combination therapy.
PDX — frequently asked questions
What is the full form of PDX?
The full form of PDX is Patient-Derived Xenograft, a research model where human tumor tissue is implanted into immunodeficient mice for studying cancer and testing treatments.
How are PDX models used in cancer research in India?
In India, PDX models are used by research institutes to test drug efficacy, study resistance mechanisms, and develop personalised treatment strategies for cancers like oral and breast cancer.
Is PDX related to any Indian exam syllabus?
Yes, PDX is relevant for NEET PG and CSIR NET as it appears in topics like oncology, preclinical models, and translational research in biotechnology and medical curricula.