Next Generation Sequencing
Full Form of NGS
What is NGS?
Next Generation Sequencing (NGS) is a high-throughput DNA sequencing technology that enables rapid and cost-effective analysis of entire genomes, exomes, or targeted gene panels. Unlike traditional Sanger sequencing, which processes one DNA fragment at a time, NGS parallelizes millions of sequencing reactions simultaneously, drastically reducing time and cost. In India, NGS is increasingly used in clinical diagnostics for genetic disorders, cancer genomics, infectious disease surveillance, and pharmacogenomics. It is a cornerstone of precision medicine initiatives and agricultural genomics research, with centres like the CSIR-Institute of Genomics and Integrative Biology (IGIB) and the National Institute of Biomedical Genomics (NIBMG) leading applications. The technology is extensively taught in postgraduate biotechnology and life science curricula and is a key topic in competitive exams such as CSIR NET, GATE Biotechnology, and ICMR JRF. NGS has also enabled large-scale population genomics projects in India, including the Genome India Project, which aims to catalog genetic diversity. Its role in identifying rare mutations and pathogens makes it vital for public health responses, such as tracking variants during the COVID-19 pandemic.
NGS का फुल फॉर्म
अगली पीढ़ी का अनुक्रमण
Example
The hospital used NGS to identify the rare genetic mutation causing the patient’s neurological disorder within a week.