Methotrexate
Full Form of MTX
What is MTX?
Methotrexate (MTX) is a chemotherapy agent and immunosuppressant drug widely used in India for treating various cancers, including leukemia, lymphoma, and solid tumors, as well as autoimmune diseases such as rheumatoid arthritis, psoriasis, and Crohn's disease. It works by inhibiting dihydrofolate reductase, an enzyme essential for DNA synthesis, thereby suppressing rapid cell division. In the Indian healthcare system, MTX is a cost-effective and commonly prescribed medicine, often administered in low doses for chronic autoimmune conditions and in high doses for chemotherapy protocols. It is available in oral tablets (2.5 mg), injections, and infusions, and is frequently used in combination regimens under medical supervision. The drug requires careful monitoring due to potential side effects like hepatotoxicity and myelosuppression. MTX is a critical subject for medical, pharmacy, and nursing students in India, appearing in licensing exams like AIIMS, NEET PG, and GPAT, where its mechanism, indications, and adverse effects are frequently tested. Understanding MTX is also important for patients and caregivers managing long-term therapy for cancer or autoimmune disorders.
MTX का फुल फॉर्म
मेथोट्रेक्सेट
Example
The rheumatologist prescribed MTX 15 mg weekly for the patient's active rheumatoid arthritis.