Intravenous Immunoglobulin
Full Form of IVI
What is IVI?
Intravenous Immunoglobulin (IVI) is a blood product administered intravenously to patients with antibody deficiencies, autoimmune disorders, or severe infections. It contains pooled immunoglobulins (antibodies) extracted from thousands of healthy donors, providing passive immunity. In India, IVI is used in hospitals and clinics to treat conditions such as primary immunodeficiency syndromes, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and Kawasaki disease. It is also employed off-label for certain neurological and haematological disorders. The therapy is typically given as a slow infusion over several hours in a controlled medical setting, with monitoring for adverse reactions like headache, fever, or allergic responses. The high cost and limited availability of IVI in rural India pose challenges, but government schemes and insurance coverage have improved access. For medical aspirants preparing for NEET or AIIMS, understanding IVI’s role as an immunoglobulin replacement therapy is essential for immunology and pharmacology questions. Its mechanism involves neutralising pathogens, modulating immune responses, and reducing inflammation. IVI remains a critical, life-saving intervention in Indian tertiary care hospitals, especially for paediatric and transplant patients.
IVI का फुल फॉर्म
अंतःशिरा इम्यूनोग्लोबुलिन
Example
The paediatrician prescribed IVI for the child with primary immunodeficiency to prevent recurrent infections.