Immunoglobulin G
Full Form of IGG
What is IGG?
Immunoglobulin G (IgG) is the most abundant antibody isotype found in human blood, constituting approximately 75% of serum immunoglobulins. It plays a central role in the adaptive immune system by neutralizing pathogens such as bacteria, viruses, and toxins. In India, IgG testing is widely employed for serological surveys, particularly for diseases like COVID-19, dengue, and hepatitis, to assess past infection or vaccination response. It is also used in diagnosing autoimmune disorders and monitoring immunoglobulin deficiencies. Clinicians and diagnostic laboratories across the country rely on IgG assays to confirm prior exposure rather than acute infection. The test is fundamentally important for public health initiatives, such as the Indian Council of Medical Research’s serosurveys, which help estimate population immunity levels. For students preparing for medical entrance exams like NEET and AIIMS, understanding IgG structure, function, and clinical significance is essential, as it frequently appears in immunology and microbiology sections. IgG is the only antibody that can cross the placenta, providing passive immunity to newborns—a key concept for paediatric questions. Additionally, its four subclasses (IgG1–IgG4) have distinct roles and are tested in certain allergic and immunodeficiency panels. In routine practice, IgG levels are measured using techniques like ELISA and nephelometry. Overall, IgG is a cornerstone of humoral immunity, and its assessment is a routine yet critical tool in India’s healthcare system.
IGG का फुल फॉर्म
इम्युनोग्लोबुलिन जी
Example
The doctor advised an IgG antibody test to confirm whether the patient had been previously exposed to the dengue virus.