Hepatitis Delta Virus
Full Form of HDV
What is HDV?
Hepatitis Delta Virus (HDV) is a defective RNA virus that requires the presence of Hepatitis B Virus (HBV) for its replication and transmission. It causes the most severe form of viral hepatitis in humans, often leading to rapid progression to cirrhosis and hepatocellular carcinoma. In India, HDV infection is a significant public health concern, particularly among patients already infected with HBV. It is transmitted through contact with infected blood or bodily fluids, similar to HBV. Diagnosis is typically done through serological tests detecting anti-HDV antibodies or HDV RNA. The virus is most prevalent in the Amazon basin, parts of Africa, the Middle East, and Asia, including India. Treatment options are limited; pegylated interferon alpha is the only approved therapy, though newer antivirals are under development. Prevention primarily relies on HBV vaccination, as immunity against HBV prevents HDV infection. In Indian medical examinations such as NEET PG or AIIMS PG, HDV is a frequently tested topic in virology and hepatology, especially regarding its unique defective nature and clinical outcomes. Awareness and early detection are critical to managing the burden of this severe liver disease in India.
HDV का फुल फॉर्म
हेपेटाइटिस डेल्टा वायरस
Example
The patient with chronic HBV infection was also found to have HDV co-infection, which significantly increased his risk of liver failure.