Guillain-Barré Syndrome
Full Form of GBS
What is GBS?
Guillain-Barré Syndrome (GBS) is a rare but serious autoimmune disorder in which the body's immune system mistakenly attacks the peripheral nervous system, leading to muscle weakness, numbness, and in severe cases, paralysis. It often follows an infectious illness, such as a respiratory or gastrointestinal infection, or in some cases, vaccination. In India, GBS has drawn attention due to sporadic outbreaks, particularly linked to contaminated water or foodborne infections, and is a recognized neurological emergency requiring prompt hospitalization and treatment with intravenous immunoglobulin or plasmapheresis. The condition can affect individuals of any age, but incidence peaks in adults and older people. Symptoms usually begin with tingling or weakness in the legs, progressing upward over days to weeks. Diagnosis is confirmed through lumbar puncture, nerve conduction studies, and clinical evaluation. GBS is a common topic in Indian medical entrance exams like NEET PG and AIIMS, where questions focus on its pathophysiology, diagnostic criteria, and management. Recovery can take months, and about 80% of patients eventually regain independent ambulation, though some may have residual weakness. Awareness among Indian healthcare providers is critical for early intervention to reduce complications like respiratory failure.
GBS का फुल फॉर्म
गुइलेन-बैरे सिंड्रोम
Example
The neurologist admitted the patient with ascending paralysis and suspected GBS, ordering a lumbar puncture and nerve conduction studies.