Vascular Endothelial Growth Factor
Full Form of VEGF
What is VEGF?
Vascular Endothelial Growth Factor (VEGF) is a signaling protein that plays a crucial role in the formation of new blood vessels, a process known as angiogenesis. It is produced by cells in response to low oxygen levels and stimulates the growth of blood vessels to restore oxygen supply. In the Indian medical context, VEGF is extensively studied and targeted in the treatment of cancers (e.g., breast, lung, colorectal) and eye diseases such as diabetic retinopathy and age-related macular degeneration, which are prevalent due to India's high diabetes burden. VEGF antagonists, like bevacizumab and ranibizumab, are used in therapies to inhibit abnormal blood vessel growth. The factor is also relevant in wound healing and tissue repair. In exams like NEET PG and AIIMS, VEGF is a key topic in biochemistry and pathology, often queried for its role in tumor angiogenesis and clinical applications. Its regulation and signaling pathways (via VEGFR receptors) are fundamental to understanding modern targeted therapies and diagnostics in India's growing biomedical research sector.
VEGF का फुल फॉर्म
वैस्कुलर एंडोथीलियल ग्रोथ फैक्टर
Example
In India, ophthalmologists often prescribe anti-VEGF injections for patients with diabetic macular edema to prevent vision loss.