Interferon
Full Form of IFN
What is IFN?
Interferons (IFNs) are a group of signaling proteins released by host cells in response to the presence of several viruses, bacteria, parasites, and also tumor cells. They belong to the class of cytokines and are crucial for the innate immune response. In medical practice, interferons are used as therapeutic agents to treat viral infections such as hepatitis B, hepatitis C, and certain cancers like multiple myeloma and melanoma. In India, IFN therapy has been a key part of managing chronic viral hepatitis, especially before the advent of direct-acting antivirals. They are typically administered via injection under medical supervision. Interferons function by interfering with viral replication, activating immune cells like natural killer cells and macrophages, and upregulating major histocompatibility complex molecules. Despite their efficacy, they can cause side effects such as flu-like symptoms, fatigue, and depression. For competitive exams like NEET PG, understanding the mechanism and clinical applications of interferons is important. They remain a classic example of biological response modifiers in immunology and pharmacology syllabi.
IFN का फुल फॉर्म
इंटरफेरॉन
Example
The patient with chronic hepatitis C was started on pegylated IFN therapy combined with ribavirin.